A beautiful, natural look with fillers takes a personalized approach—These sister products are excellent for smoothing moderate to deep smile lines and facial folds with gorgeous, fine-tuned results.
La Jolla Cosmetic Surgery Centre & Medical Spa 9850 Genesee Ave Suite #130
La Jolla, CA 92037 Call: (858) 452-1981Text: (858) 203-2944 Monday–Friday: 7:30 a.m.–6 p.m.
Restylane Defyne & Refyne in San Diego
When it comes to getting a totally natural look with fillers, one size does NOT fit all—and the popular filler manufacturer Restylane understands this. The most recent additions to the Restylane® family, Restylane Refyne and Restylane Defyne, are great options to smooth moderate to deep facial lines and folds, and we’re proud to offer them both at LJC.
How are Refyne and Defyne different from regular Restylane?
All Restylane fillers are gels made from hyaluronic acid (HA), a naturally occurring substance in the skin that can hold many times its weight in water and works fabulously to help restore facial volume and smooth lines and wrinkles.
Refyne and Defyne are made with the latest technology, XpresHAn™, which blends the HA particles in a way that lets the filler move more naturally with your facial expressions. While your injectable provider’s skill matters most in achieving an effective, natural-looking result, Refyne and Defyne are designed to help avoid the stiff or unnatural feeling that can sometimes occur with deeper filler injections in parts of the face that move frequently and dynamically.
Restylane® Defyne Before & After Photos
Keep in mind that each patient is unique and your results may vary.
Refyne and Defyne are very similar products, with slightly different consistencies. Defyne is slightly thicker and therefore can be injected a little more deeply to treat more severe folds (it may help to think the “D” in Defyne stands for “deep”).
Our plastic surgeons and PA/RN providers use a very thin, short needle to inject the filler, which is infused with the mild anesthetic lidocaine to enhance comfort. Most patients experience a brief pinching sensation and pressure during treatment. Numbing cream may be used to help with discomfort.
Don't Take Our Word for It, Trust 85 Verified Restylane® Defyne & Refyne Reviews
95% Patient Satisfaction
Based on 85 ratings
Verified Reviews & Ratings by
5 stars (71)
83.53%
4 stars (10)
11.76%
3 stars (2)
2.35%
2 stars (1)
1.18%
1 star (1)
1.18%
Jul 26, 2022
The process from start to finish was amazing! As a first timer, everyone made me feel comfortable an…*
Jul 23, 2022
Dr Riedler was absolutely amazing. I had many cc of filler and it was pain free. She explained the p…*
Jul 22, 2022
There was very little discomfort with my procedures and was injected very skillfully*
* These are actual patient comments verified by a 3rd party. The claims made represent the opinion of the author.
Enjoy pain-free filler injections with add-on option PRO-NOX™
Every patient deserves a comfortable experience, so we now offer an add-on option to use PRO-NOX™, a self-administered nitrous oxide (laughing gas) system that allows you to be in full control of your comfort.
If at any point you feel you need something to take the edge off, simply breathe through the PRO-NOX™ mouthpiece for instant relief from pain and anxiety. Unlike oral pain medication, PRO-NOX™ takes effect in seconds, but these effects wear off minutes. You can safely drive and return to your normal routine without worrying about side effects.
Ask us about adding PRO-NOX™ to your treatment at your consultation, or contact us for more information!
Restylane Refyne/Defyne both typically last about 9 to 12 months. However, everyone is different. Some patients are happy with their results for longer than a year, while others choose to repeat treatment more frequently.
Hyaluronic acid fillers, such as Restylane products, are safely absorbed by the body and metabolized and eliminated naturally over time. If you’re interested in a filler that will last longer than 12 months, you may consider Sculptra.
Your Safety Is Our #1 Priority
Since 1988, more than 36,000 patients have had safe, successful procedures at La Jolla Cosmetic Surgery Centre & Medical Spa.
We reserve time in our schedules for fillers and BOTOX appointments. We can also see you during your lunch break, or in the evening on certain days of the week. Call
(858) 452-1981 to check availability.
Choosing the right filler for your needs
Yes, there are a whole lot of fillers on the market—and choosing the right one takes an experienced provider’s help. LJC certified aesthetic nurse specialist Brittany Haley, RN-BSN, explains how she approaches filler choices.
Design the New You
Not sure how to get the look you want? Tell us about your goals, and we’ll show you the possibilities.